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MMP-8 also known as matrix metalloproteinase-8 or collagenase-2 is recognized for its enzymatic abilities particularly its ability to break down fibrillar types I II and III collagen This enzymatic activity suggests that MMP-8 plays an important role in the remodeling and turnover of collagen-rich tissues such as connective tissue cartilage and bone MMP-8 Protein Human (HEK293 His) is the recombinant human-derived MMP-8 protein expressed by HEK293 with C-10 His labeled tag
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Membrane Preparations for Vesicular Transport Assays (VT) are suitable for general drug-efflux transporter interaction studies. Both substrate and inhibitor interactions can be assessed using vesicles. Membrane Preparations for ATPase Assays are suitable for drug-efflux transporter interaction studies based on ATPase activity determination and could be used for differentiation between transporter substrates and inhibitors. Control Membranes with no- or significantly lower transporter activity are available for both Vesicular Transport and ATPase Assays.
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Alternative name: NGF 2.5S. Purity: ≥90% (SDS-PAGE). Formulation: Lyophilized. Source: Isolated from mouse submaxillary glands by a modification of the procedure described by T. Darling, et al.; Cell Culture Meth. Mol. Cell Biol. 4, 79 (1984). Long Term Storage: -20°C.
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PDGF-BB Protein Rat is a member of PDGF family which promotes cell proliferation survival and migration through binding to the tyrosine kinase PDGF receptor
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CD4 Protein is expressed on the surface of helper T cells It plays a key role in immune responses by binding to major histocompatibility complex class II molecules on antigen-presenting cells facilitating T cell activation and cytokine production CD4 Protein is also involved in immune regulation and tolerance Understanding its functions can aid in developing therapies for autoimmune diseases and immunodeficiencies CD4 Protein Rat (HEK293 His) is the recombinant rat-derived CD4 protein expressed by HEK293 with C-His labeled tag
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The Meso Scale Discovery U-PLEX Human FGF Basic Assay is a multiplex immunoassay kit for quantifying human FGF basic in various biological matrices It uses electrochemiluminescence detection offering high sensitivity a dynamic range of up to 5 logs and low sample consumption Requiring 50 L of sample it is compatible with Meso Scale Discovery instruments like the MESO QuickPlex SQ 120 series The kit includes a 96-well plate with capture antibodies detection antibodies with electrochemiluminescent tags and calibrators and controls for standard curve generation and assay validation
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The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
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